RCT A - Atrial Flutter without Hydrops

RCT C - Treatment Arms

RCT C ARM 1: DIGOXIN plus FLECAINIDE

0.5 mg Digoxin q 8hrs

(total 4 doses over 32 hrs) 

Aim: therapeutic maternal trough level of 1.5-2.0 ng/ml or 1.9-2.6 nmol/L

plus

100 mg Flecainide (TID) (300 mg/day)

 

RCT C ARM 2: DIGOXIN plus SOTALOL

0.5 mg Digoxin q 8hrs

(total 4 dosesover 32 hrs) 

Aim: therapeutic maternal trough level of 1.5-2.0 ng/ml or 1.9-2.6 nmol/L

plus

160 mg Sotalol (BID) (320 mg/day)

 

Note: See study protocol for specific treatment information and recommendations.

Note: See study protocol for specific treatment information and recommendations.

RCT C - SVT with Hydrops

RCT C Care Map

Screening of study eligibility

Randomization by sites in REDCap

Treatment start

Clinical and ultrasound assessments

Use recommended 1st line therapy for 3 to 7 days unless earlier changes are clinically indicated

A) to d) represent possible early outcome scenarios and recommended treatment adjustments 

Note: Please refer to your study protocol and study documents for country specific procedures and guidelines. The on-line text is a general information guide only.